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Lynparza is an oral medication used to treat some types of cancer by blocking the action of the PARP enzyme, preventing cancer cells from multiplying. It is used for ovarian, breast, and pancreatic cancer patients with a BRCA gene mutation or triple-negative breast cancer. Lynparza has possible side effects such as fatigue, nausea, diarrhea, and loss of appetite; it can also increase the risk of other cancers such as leukemia. Pregnant or breastfeeding women should not use Lynparza. The cost can be high, but there are programs to help patients. Lynparza is an important targeted therapy treatment option for cancers with a genetic component.
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Perjeta is a monoclonal antibody used in the treatment of HER2-positive breast cancer. It works by preventing the HER2 receptor from interacting with other receptors. It belongs to the class of drugs known as HER2 inhibitors and is FDA approved to be used in combination with Herceptin and chemotherapy. Perjeta has been shown to significantly improve progression-free survival in patients with metastatic HER2-positive breast cancer. It is administered intravenously once every three weeks and can be continued up to a year or more in certain patients who are responding well to treatment. Common side effects of Perjeta include fatigue, nausea, diarrhea, and hair loss.
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Tecentriq (Atezolizumab) is an immune checkpoint inhibitor used in conjunction with chemotherapy or other cancer medications to attack cancer cells. By blocking PD-L1, a protein on some cancer cells, Tecentriq allows the immune system to recognize and target cancer cells. Clinical trials show that Tecentriq extends survival and improves outcomes in patients with lung cancer, bladder cancer, and triple-negative breast cancer. Tecentriq is generally well-tolerated, administered intravenously once every three or four weeks, and monitored for potential side effects. Tecentriq is FDA-approved for several types of cancer, making it a promising treatment option for many cancer patients.
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