Accrufer, whose generic name is ferric maltol, is a prescription medication used in the treatment of iron-deficiency anemia in adults with inflammatory bowel disease (IBD), such as Crohn’s disease or ulcerative colitis, who have had an inadequate response to oral iron supplements. It is specifically designed to address iron deficiency in individuals with IBD, a condition that can result from chronic inflammation and impaired iron absorption in the gastrointestinal tract. Here is a detailed description of Accrufer:

Drug Class: Accrufer belongs to the class of medications known as iron supplements. However, it is distinct from traditional oral iron supplements due to its unique formulation as ferric maltol.

Indications: Accrufer is primarily prescribed for the treatment of iron-deficiency anemia in adults with inflammatory bowel disease (IBD) when oral iron supplementation alone has proven to be insufficient in raising hemoglobin levels and replenishing iron stores.

Mechanism of Action: Ferric maltol, the active ingredient in Accrufer, is a complex of ferric iron (Fe3+) and maltol, a compound that helps to solubilize and stabilize the iron. This unique formulation is designed to improve the absorption of iron in the gut, which is often compromised in individuals with IBD due to inflammation and damage to the intestinal lining. By providing a more bioavailable form of iron, Accrufer helps to correct iron deficiency anemia in these patients.

Dosage and Administration: The dosage of Accrufer is typically based on the individual patient’s iron deficiency status and the severity of their anemia. It is available in tablet form and is taken orally with or without food, as directed by a healthcare provider. The dosage and duration of treatment should be determined by a healthcare professional.

Effectiveness: Accrufer has been shown to be effective in improving hemoglobin levels and replenishing iron stores in individuals with iron-deficiency anemia associated with inflammatory bowel disease.

Side Effects: Like all medications, Accrufer may have side effects. Common side effects may include gastrointestinal symptoms such as diarrhea, abdominal pain, and nausea. However, these side effects are generally less common than with traditional oral iron supplements.

Contraindications: Accrufer should not be used in individuals with known hypersensitivity to ferric maltol or any of its components. It is also not recommended for the treatment of iron-deficiency anemia in individuals without inflammatory bowel disease.

Consultation with a Healthcare Provider: Before starting Accrufer, individuals should consult with their healthcare provider to determine the appropriate treatment plan, including dosage and monitoring. It is essential to provide a complete medical history and inform the healthcare provider about any other medications or supplements being taken to prevent potential interactions.

Accrufer is a valuable medication for addressing iron-deficiency anemia in individuals with inflammatory bowel disease who have not responded adequately to standard oral iron supplements. It should only be used under the supervision and guidance of a qualified healthcare professional who can assess the individual’s specific medical condition and needs.