Chemical name: 2,2′-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
Formula: C17H19N5

ARIMIDEX 1mg, manufactured by AstraZeneca, is a potent aromatase inhibitor designed to combat estrogen-related side effects in hormone-sensitive conditions such as breast cancer. Each package of ARIMIDEX contains 28 pills, with each pill containing 1mg of Anastrozole, the active ingredient.

Key Features:

1. Aromatase Inhibition: ARIMIDEX contains Anastrozole, a selective aromatase inhibitor that effectively suppresses the conversion of androgens into estrogen. By inhibiting aromatase activity, Anastrozole reduces circulating estrogen levels, making it an essential component of hormone therapy in estrogen receptor-positive breast cancer.
2. Breast Cancer Treatment: ARIMIDEX is indicated for the adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer. It is also used as a first-line therapy for metastatic breast cancer in postmenopausal women. By blocking estrogen production, ARIMIDEX helps slow or halt the progression of hormone-sensitive breast tumors.
3. Estrogen Suppression: Anastrozole effectively suppresses estrogen levels in postmenopausal women, thereby depriving estrogen-dependent breast cancer cells of their growth stimulus. This leads to tumor regression and improved clinical outcomes in patients with hormone receptor-positive breast cancer.
4. Reduced Risk of Recurrence: ARIMIDEX therapy has been shown to reduce the risk of breast cancer recurrence and improve disease-free survival in postmenopausal women with early-stage breast cancer. It is often prescribed as part of a comprehensive treatment regimen following surgery, radiation, or chemotherapy.
5. Well-Tolerated: ARIMIDEX is generally well-tolerated, with most adverse effects being mild to moderate in severity. Common side effects may include hot flashes, joint pain, fatigue, and nausea. Serious adverse effects such as osteoporosis and cardiovascular events are rare but may occur with long-term use.

Usage Guidelines:

• ARIMIDEX should be taken orally once daily, preferably at the same time each day.
• The recommended dosage of ARIMIDEX is 1mg/day, administered as a single dose.
• Treatment duration may vary depending on the specific indication and individual patient response. Patients should follow the prescribed treatment regimen and adhere to regular follow-up appointments with their healthcare provider.

ARIMIDEX 1mg (Anastrozole) stands as a cornerstone in the treatment of hormone receptor-positive breast cancer, offering patients a potent and well-tolerated therapy for reducing estrogen levels and improving clinical outcomes. With its proven efficacy, convenient dosing regimen, and favorable safety profile, ARIMIDEX plays a crucial role in the management of hormone-sensitive breast cancer in postmenopausal women.