Overview: Caberlin is a medication that contains the active ingredient Cabergoline. It belongs to a class of drugs known as dopamine receptor agonists and is primarily used in the treatment of disorders associated with abnormally high levels of prolactin, a hormone produced by the pituitary gland.

Active Ingredient:

• Cabergoline: Caberlin contains Cabergoline, which is a dopamine receptor agonist. It works by stimulating dopamine receptors in the brain, thereby inhibiting the secretion of prolactin from the pituitary gland.

Indications: Caberlin (Cabergoline) is primarily indicated for:

1. Hyperprolactinemia: It is used for the treatment of hyperprolactinemia, a condition characterized by abnormally high levels of prolactin in the blood. Hyperprolactinemia can lead to various symptoms, including irregular menstrual periods, infertility, and breast milk production in non-pregnant individuals.
2. Prolactinomas: Caberlin is also used for the treatment of prolactinomas, which are benign tumors of the pituitary gland that secrete excessive amounts of prolactin.

Mechanism of Action: Cabergoline exerts its therapeutic effects by acting as a dopamine receptor agonist. Dopamine is a neurotransmitter that inhibits the secretion of prolactin from the pituitary gland. By stimulating dopamine receptors, Cabergoline suppresses the production and release of prolactin, thereby normalizing prolactin levels in the blood.

Dosage and Administration: The dosage of Caberlin (Cabergoline) is determined by the healthcare provider based on the severity of the condition and individual patient response. It is typically taken orally in the form of tablets, with or without food. The dosage regimen may vary depending on the specific indication being treated.

Potential Side Effects: Common side effects of Cabergoline may include nausea, headache, dizziness, fatigue, and constipation. Some patients may experience symptoms such as orthostatic hypotension (low blood pressure upon standing) and gastrointestinal disturbances. Serious side effects such as heart valve disorders and psychiatric disturbances are rare but may occur with prolonged use or at high doses.

Precautions:

• Cardiac Monitoring: Cabergoline may rarely cause cardiac valve disorders, and periodic cardiac monitoring may be recommended during long-term treatment.
• Pregnancy and Breastfeeding: Cabergoline should not be used during pregnancy unless clearly necessary, as it may harm the developing fetus. It is also not recommended for use during breastfeeding.
• Elderly Patients: Caution is advised when prescribing Cabergoline to elderly patients, as they may be more susceptible to certain side effects, such as orthostatic hypotension.

Prescription Requirement: Caberlin (Cabergoline) is available only with a prescription and should be used under the supervision of a qualified healthcare professional.

In conclusion, Caberlin (Cabergoline) is a dopamine receptor agonist used in the treatment of hyperprolactinemia and prolactinomas. Its mechanism of action involves stimulating dopamine receptors to inhibit prolactin secretion from the pituitary gland. While generally well-tolerated, careful monitoring for potential side effects and precautions are necessary during treatment with Cabergoline.