Description: Everolimus is a derivative of rapamycin, belonging to the class of drugs known as mTOR (mammalian target of rapamycin) inhibitors. It is available in various formulations, including oral tablets and as a component of certain drug-eluting stents.

Uses: Everolimus has multiple therapeutic uses, including:

1. Immunosuppression: Everolimus is used in transplant medicine to prevent organ rejection in kidney and liver transplant recipients.
2. Oncology: In the field of oncology, Everolimus is utilized to treat various types of cancers, including advanced renal cell carcinoma, breast cancer, pancreatic neuroendocrine tumors, and subependymal giant cell astrocytoma associated with tuberous sclerosis.

Mechanism of Action: Everolimus inhibits the activity of mTOR, a protein kinase that plays a crucial role in cell growth and proliferation. By blocking mTOR, Everolimus interferes with cancer cell division and the growth of blood vessels that support tumor development.

How to Use: The usage of Everolimus varies depending on the medical condition being treated. It is typically administered orally in the form of tablets, and the dosage is determined by the treating physician. Patients should follow their healthcare provider’s instructions carefully.

Storage Conditions: Everolimus tablets should be stored at room temperature, protected from light and moisture. It’s important to keep the medication in its original packaging.

Precautions: Patients taking Everolimus should be monitored regularly for blood counts, kidney function, and lipid levels. It is important to inform healthcare providers about all medications, including over-the-counter drugs and supplements, to avoid potential interactions.

Contraindications: Everolimus is contraindicated in individuals with known hypersensitivity to the drug. It is also not recommended for use in pregnant women due to potential harm to the fetus.

Drug Interactions: Everolimus may interact with various medications, and healthcare providers should be aware of the patient’s complete medication history to avoid potential adverse effects.

Side Effects: Common side effects of Everolimus may include mouth sores, rash, diarrhea, fatigue, and changes in blood counts. Serious side effects such as infections, pneumonitis, and renal failure can also occur.

It’s important to note that this information is based on the knowledge available up to January 2022, and there may have been developments or updates since then. Patients should always consult with their healthcare providers for the most current and personalized information regarding Everolimus or any other medication.