Description: Femara is the brand name for the generic drug Letrozole, which belongs to a class of medications known as aromatase inhibitors. Aromatase inhibitors are widely used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. Femara works by reducing the levels of estrogen in the body, inhibiting the conversion of androgens (male hormones) into estrogen.

Uses: Femara (Letrozole) is primarily prescribed as adjuvant therapy for postmenopausal women with hormone receptor-positive early breast cancer. It is also utilized as a first-line treatment for metastatic breast cancer in postmenopausal women. By suppressing estrogen production, Femara helps slow down or inhibit the growth of hormone-sensitive breast tumors.

Mechanism of Action: Letrozole exerts its therapeutic effect by inhibiting the activity of the enzyme aromatase, which is responsible for the conversion of androgens into estrogen in postmenopausal women. Lowering estrogen levels in the body is crucial for impeding the stimulation of hormone-sensitive breast cancer cells, ultimately slowing down or arresting their growth.

How to Use: Femara is typically administered orally, usually as a daily tablet. The dosage and duration of treatment will be determined by the treating oncologist based on the specific characteristics of the patient’s breast cancer and overall health. It is important to follow the prescribed dosage and administration instructions carefully.

Important Safety Information:

• Before starting Femara, inform your healthcare provider about any allergies, pre-existing medical conditions, or medications you are currently taking.
• Femara is intended for use in postmenopausal women only.
• Regular monitoring of bone health may be recommended during treatment.

Precautions:

• Pregnant women or those planning to become pregnant should avoid using Femara, as it may cause harm to the developing fetus.
• Inform your healthcare provider of any liver problems or conditions affecting bone health.

Interactions: Femara may interact with certain medications, and it is crucial to inform your healthcare provider about all the medications, supplements, and herbal products you are taking.

Contraindications: Femara is contraindicated in premenopausal women, individuals with a known allergy to Letrozole or any of its components, and pregnant or breastfeeding women.

Side Effects: Common side effects of Femara may include:

• Hot flashes
• Joint pain
• Bone pain
• Nausea
• Fatigue

It is essential to report any persistent or severe side effects to your healthcare provider promptly. Regular medical check-ups are crucial for monitoring the effectiveness and safety of Femara treatment.