Indications:

• GLIFOR, containing the active ingredient metformin, is a medication primarily used in the management of type 2 diabetes mellitus. It is often prescribed alongside diet and exercise to improve blood sugar control in patients with diabetes.

Mechanism of Action:

• Metformin belongs to the class of biguanide medications and works by reducing glucose production in the liver and improving insulin sensitivity in peripheral tissues. It also helps decrease intestinal glucose absorption, leading to lower blood sugar levels.

Administration:

• GLIFOR is typically administered orally in the form of tablets. The dosage and treatment plan are individualized for each patient and are determined based on factors such as the severity of diabetes, kidney function, and response to treatment.

Dosage Forms:

• GLIFOR may be available in various dosage forms, including immediate-release tablets, extended-release tablets, and oral solution.

Dosage and Treatment Plan:

• The dosage of GLIFOR is usually initiated at a low dose and gradually increased over time to achieve optimal blood sugar control while minimizing side effects. The treatment plan may also include regular monitoring of blood glucose levels and adjustments to diet and exercise.

Side Effects:

• Common side effects of GLIFOR may include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal discomfort. These side effects are usually mild and transient and may improve with continued use. Rare but serious side effects may include lactic acidosis, a potentially life-threatening condition.

Precautions:

• GLIFOR should be used with caution in patients with kidney impairment, liver disease, or conditions predisposing to lactic acidosis. It is important to assess kidney function before initiating treatment and periodically thereafter.

Consultation with a Healthcare Provider:

• Before starting GLIFOR treatment, patients should have a comprehensive consultation with their healthcare provider. The healthcare team will assess the patient’s medical history, current medications, and overall health to determine the suitability of metformin therapy.

Pregnancy and Contraindications:

• GLIFOR may be used during pregnancy under the guidance of a healthcare provider, especially in cases of gestational diabetes or polycystic ovary syndrome (PCOS). However, it is generally contraindicated in patients with severe kidney impairment, liver disease, or conditions predisposing to lactic acidosis.

Patients taking GLIFOR should be educated about the importance of regular monitoring of blood sugar levels, adherence to treatment, and lifestyle modifications to optimize diabetes management. They should also be advised to seek medical attention if they experience any unusual symptoms or side effects while taking the medication.