Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
KAMAGRA-50
Description:
Kamagra-50 is a pharmaceutical product containing the active substance sildenafil. It is primarily used for the treatment of erectile dysfunction (ED), a common condition characterized by the inability to achieve or maintain an erection sufficient for sexual activity. Sildenafil belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors, which work by increasing blood flow to the penis during sexual stimulation, resulting in improved erectile function.
Key Points:
- Active Ingredient:
- Sildenafil: A potent selective inhibitor of phosphodiesterase type 5 (PDE5), which enhances the effects of nitric oxide (NO) in the corpus cavernosum of the penis, leading to smooth muscle relaxation and increased blood flow, ultimately facilitating erections.
- Indications:
- Kamagra-50 is indicated for the treatment of erectile dysfunction (ED) in adult men, defined as the consistent inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance.
- Mechanism of Action:
- Sildenafil acts by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which degrades cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. By blocking PDE5, sildenafil increases cGMP levels, leading to smooth muscle relaxation, vasodilation, and increased blood flow to the penis, resulting in improved erectile function.
- Dosage Form:
- Kamagra-50 is available as oral tablets, typically supplied in blister packs containing a specific number of pills, each containing 50 mg of sildenafil.
- Dosage and Administration:
- The recommended dosage of Kamagra-50 is one 50 mg tablet taken orally approximately 1 hour before anticipated sexual activity. The dosage may be adjusted based on individual response and tolerability, with a maximum recommended dose of 100 mg per day. It is important to avoid exceeding the maximum recommended dose to minimize the risk of adverse effects.
- Onset and Duration of Action:
- Sildenafil is rapidly absorbed after oral administration, with peak plasma concentrations reached within 30 to 120 minutes. The onset of action varies among individuals but is generally observed within 30 to 60 minutes after ingestion. The duration of action is typically 4 to 6 hours, during which time sexual stimulation is required to achieve an erection.
- Precautions:
- Kamagra-50 should be used with caution in patients with underlying cardiovascular disease, liver or kidney impairment, or anatomical deformities of the penis. It should not be used concomitantly with nitrates or nitric oxide donors due to the risk of severe hypotension.
- Possible Side Effects:
- Common side effects of sildenafil may include headache, flushing, dyspepsia, nasal congestion, and visual disturbances. Rare but serious side effects such as priapism (prolonged erection lasting more than 4 hours) and sudden vision loss may occur and require immediate medical attention.
- Manufacturer:
- Kamagra-50 is manufactured by Ajanta Pharma, a reputable pharmaceutical company known for its high-quality generic medications.
Note: Kamagra-50 offers a convenient and effective treatment option for men with erectile dysfunction, providing rapid onset of action and prolonged duration of effect. Patients should be advised to use sildenafil as directed by a healthcare professional and to seek medical attention if they experience any concerning side effects or if their erections persist for longer than 4 hours. It is important to discuss the potential risks and benefits of sildenafil therapy with a healthcare provider to ensure safe and appropriate use.
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