Chemical name: 4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile;
Formula: C17H11N5
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
LETROMINA 2.5mg – ALPHA PHARMA
Letromina, manufactured by Alpha Pharma, is a medication available in the form of tablets, with each tablet containing 2.5 mg of the active substance, letrozole. Here’s a detailed description:
1. Active Substance: Letrozole
- Letromina contains letrozole as its primary active ingredient. Letrozole belongs to a class of medications known as aromatase inhibitors. It works by inhibiting the enzyme aromatase, which is involved in the production of estrogen. By reducing estrogen levels in the body, letrozole is effective in treating hormone receptor-positive breast cancer in postmenopausal women.
2. Medical Indications:
- Letromina tablets are primarily indicated for the treatment of hormone receptor-positive breast cancer in postmenopausal women. It may be used as adjuvant therapy following surgery or as first-line or second-line treatment for advanced breast cancer that has spread to other parts of the body.
3. Dosage and Administration:
- The recommended dosage of Letromina tablets is typically 2.5 mg once daily, administered orally with or without food. The duration of treatment and dosage may vary depending on factors such as the stage of breast cancer, response to therapy, and tolerance to the medication. It is important to follow the prescribed dosage and administration instructions provided by a healthcare professional.
4. Manufacturer:
- Letromina tablets are manufactured by Alpha Pharma, a pharmaceutical company known for producing a wide range of medications, including anabolic steroids, hormones, and anticancer drugs. Alpha Pharma is recognized for its commitment to quality and adherence to good manufacturing practices.
5. Side Effects:
- Common side effects of Letromina may include hot flashes, fatigue, headache, nausea, and musculoskeletal pain. Some patients may also experience vaginal dryness, mood changes, or hair thinning. Rare but serious side effects such as bone fractures, cardiovascular events, or liver toxicity may occur and should be promptly reported to a healthcare provider.
6. Precautions:
- Letromina should be used with caution in patients with pre-existing medical conditions such as liver disease, osteoporosis, or cardiovascular disease. It is important to inform the healthcare provider about any medications or supplements being taken, as they may interact with letrozole.
7. Drug Interactions:
- Letromina may interact with certain medications, including tamoxifen, estrogen-containing products, and medications that affect liver enzymes, leading to potential adverse effects or reduced efficacy. It is essential to disclose all medications and supplements to a healthcare provider before starting treatment with Letromina.
Letromina, containing letrozole as the active substance and manufactured by Alpha Pharma, is an essential therapeutic option for the treatment of hormone receptor-positive breast cancer in postmenopausal women. With its efficacy, reliability, and manageable side effect profile, Letromina plays a crucial role in improving patient outcomes and quality of life in individuals with breast cancer.
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