Levotiron 100, manufactured by Abdi Ibrahim, is a medication containing the active substance levothyroxine sodium. It is primarily used in the treatment of hypothyroidism, a condition characterized by an underactive thyroid gland that does not produce enough thyroid hormone. Here’s a detailed description:

Key Features:

1. Indications: Levotiron 100 is indicated for the treatment of hypothyroidism, a condition in which the thyroid gland fails to produce sufficient thyroid hormone. It is also used for the prevention and treatment of goiter (enlarged thyroid gland) and as adjunctive therapy in the management of thyroid cancer.
2. Active Substance:
   • Levothyroxine Sodium: Levothyroxine is a synthetic form of the thyroid hormone thyroxine (T4). It acts as a replacement for endogenous thyroid hormone in patients with hypothyroidism, helping to restore normal thyroid hormone levels and alleviate symptoms associated with thyroid hormone deficiency.
3. Dosage Form: Levotiron 100 is available in tablet form, with each tablet typically containing 100 micrograms of levothyroxine sodium. It is commonly supplied in blister packs containing 100 tablets.
4. Dosage and Administration: The dosage of Levotiron 100 is individualized based on factors such as the patient’s age, weight, severity of hypothyroidism, and response to treatment. It is usually taken orally once daily, preferably on an empty stomach, at least 30 minutes to 1 hour before breakfast. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed.
5. Mechanism of Action: Levothyroxine exerts its pharmacological effects by acting as a synthetic replacement for endogenous thyroid hormone. Once absorbed into the bloodstream, levothyroxine is converted into triiodothyronine (T3) in peripheral tissues, where it exerts its metabolic and physiological effects. These effects include regulation of metabolism, growth, development, and energy expenditure.
6. Benefits:
   • Correction of Hypothyroidism: Levotiron 100 helps correct the deficiency of thyroid hormone in patients with hypothyroidism, leading to improvements in symptoms such as fatigue, weight gain, cold intolerance, constipation, dry skin, hair loss, and menstrual irregularities.
   • Prevention of Goiter: By restoring normal thyroid hormone levels, Levotiron 100 helps prevent and shrink the enlargement of the thyroid gland (goiter) caused by thyroid hormone deficiency.
   • Adjunctive Therapy for Thyroid Cancer: Levotiron 100 may be used as adjunctive therapy in the management of thyroid cancer, particularly after thyroidectomy (surgical removal of the thyroid gland), to suppress the growth of residual thyroid tissue and prevent cancer recurrence.
7. Side Effects: Common side effects associated with Levotiron 100 may include:
   • Palpitations or rapid heartbeat
   • Tremors or nervousness
   • Insomnia or difficulty sleeping
   • Sweating or heat intolerance
   • Weight loss or appetite changes
   • Diarrhea or gastrointestinal upset
   • Headache or dizziness
8. Contraindications and Precautions: Levotiron 100 is contraindicated in individuals with known hypersensitivity to levothyroxine or any of its components. It should be used with caution in patients with certain medical conditions, such as cardiovascular disease, adrenal insufficiency, diabetes mellitus, or a history of thyroid cancer.
9. Storage: Levotiron 100 tablets should be stored according to the manufacturer’s instructions, typically at room temperature away from light, heat, and moisture. Unused tablets should be kept in their original blister packaging until ready for use.

As with any medication for hypothyroidism, the use of Levotiron 100 should be supervised by a qualified healthcare provider. Patients should receive education on proper dosing, potential side effects, and the importance of regular thyroid function monitoring to ensure optimal treatment outcomes and prevent complications. Close communication between patients and healthcare providers is essential for managing hypothyroidism effectively and ensuring patient safety.