Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid

MALEGRA-120

Product Overview: MALEGRA-120, manufactured by Sunrise Remedies, offers a potent formulation of sildenafil citrate to address erectile dysfunction (ED) and enhance sexual performance. Each box contains 10 tablets, each dosed at 120mg of sildenafil, providing a convenient and effective solution for individuals seeking to improve their sexual health and vitality.

Active Substance: Sildenafil Citrate: Sildenafil citrate is a phosphodiesterase type 5 (PDE5) inhibitor that works by increasing blood flow to the penis during sexual stimulation. It helps relax the smooth muscles of the blood vessels in the penis, allowing for enhanced blood flow and the attainment of a firm and lasting erection.

Mechanism of Action: MALEGRA-120 functions by inhibiting the enzyme PDE5, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. By inhibiting PDE5, sildenafil prolongs the effects of cGMP, leading to smooth muscle relaxation and increased blood flow, thus facilitating penile erection.

Clinical Applications: MALEGRA-120 is primarily used for:

1. Erectile Dysfunction (ED): MALEGRA-120 is indicated for the treatment of erectile dysfunction, a common condition characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. It helps restore erectile function and improve sexual satisfaction in affected individuals.
2. Pulmonary Arterial Hypertension (PAH): In addition to its use in treating ED, sildenafil citrate is also used to manage pulmonary arterial hypertension, a condition characterized by high blood pressure in the arteries of the lungs. MALEGRA-120 helps relax the pulmonary blood vessels, thereby reducing pulmonary arterial pressure and improving exercise capacity.

Administration and Dosage: MALEGRA-120 is administered orally, typically 30 minutes to 1 hour before anticipated sexual activity. The recommended dosage is one tablet (120mg) per day, although dosage adjustments may be made based on individual response and tolerability. It is important not to exceed the prescribed dosage to minimize the risk of adverse effects.

Manufacturer: MALEGRA-120 is manufactured by Sunrise Remedies, a reputable pharmaceutical company known for its commitment to quality and innovation. Sunrise Remedies products undergo rigorous testing and adhere to stringent manufacturing standards to ensure safety, efficacy, and consistency.

Considerations and Side Effects: While generally well-tolerated, MALEGRA-120 may cause certain side effects in some individuals, including:

• Headache
• Flushing
• Dyspepsia (indigestion)
• Nasal congestion
• Visual disturbances (such as blurred vision or changes in color vision)

Patients should be advised to seek medical attention if they experience persistent or severe side effects.

Conclusion: MALEGRA-120 from Sunrise Remedies offers a reliable and effective solution for individuals experiencing erectile dysfunction or pulmonary arterial hypertension. With its potent formulation of sildenafil citrate, MALEGRA-120 helps restore erectile function and enhance sexual performance, improving overall quality of life and sexual satisfaction. As with any medication, it is important to use MALEGRA-120 as directed by a healthcare professional and to be aware of potential side effects.