Sildenafil Citrate 100mg
Duloxetine 30mg
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid

MALEGRA-DXT

1. Active Substances:

• Duloxetine: Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used primarily to treat depression, anxiety disorders, and certain types of chronic pain conditions. It works by increasing the levels of serotonin and norepinephrine in the brain, which helps improve mood and alleviate pain.
• Sildenafil: Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED) in men. It works by inhibiting the enzyme PDE5, which regulates blood flow to the penis. By inhibiting PDE5, sildenafil enhances the erectile response to sexual stimulation by increasing blood flow to the penis.

2. Indications:

• Male Sexual Dysfunction: Malegra-DXT is indicated for the treatment of male sexual dysfunction, particularly erectile dysfunction and premature ejaculation.
• Depression and Anxiety: Duloxetine is indicated for the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other anxiety disorders.

3. Dosage:

• Each Malegra-DXT tablet contains a combination of duloxetine and sildenafil, with a total dosage of 130 mg.
• The recommended dosage and duration of treatment may vary depending on the individual patient’s response to therapy, medical history, and severity of symptoms.
• Treatment should be initiated and supervised by a qualified healthcare professional.

4. Administration:

• Malegra-DXT tablets are taken orally with a full glass of water.
• The tablets can be taken with or without food, although taking them with a high-fat meal may delay the onset of action of sildenafil.
• It is important to follow the dosage instructions provided by a healthcare professional.

5. Effectiveness:

• Malegra-DXT combines the therapeutic effects of duloxetine and sildenafil to address both erectile dysfunction and premature ejaculation in men.
• Duloxetine helps improve mood and reduce anxiety, which can contribute to sexual dysfunction, while sildenafil enhances erectile function by increasing blood flow to the penis.

6. Safety Profile:

• Malegra-DXT is generally well-tolerated when used as prescribed. Common side effects may include nausea, headache, dizziness, dry mouth, and gastrointestinal disturbances.
• Serious side effects such as serotonin syndrome, priapism (prolonged erection), and sudden hearing loss are rare but possible.
• Patients should be monitored closely for adverse reactions, especially when initiating treatment or adjusting dosage.

7. Contraindications:

• Malegra-DXT is contraindicated in patients with known hypersensitivity to duloxetine, sildenafil, or any of the excipients in the formulation.
• It should not be used in patients with severe liver or kidney impairment, uncontrolled hypertension, or recent history of stroke or heart attack.

8. Precautions:

• Malegra-DXT should be used with caution in patients with a history of bleeding disorders, seizures, or bipolar disorder.
• It should be avoided in patients taking monoamine oxidase inhibitors (MAOIs) or other medications that affect serotonin levels.

9. Storage:

• Malegra-DXT should be stored at room temperature (15°C to 30°C) in a dry place, away from moisture and heat.
• Keep the medication out of reach of children and pets.

Malegra-DXT tablets, manufactured by Sunrise Remedies, offer a convenient and effective treatment option for men with erectile dysfunction and premature ejaculation, as well as patients with depression and anxiety disorders. Treatment should be initiated and monitored by a qualified healthcare professional, and patients should be informed about potential side effects and precautions associated with the use of duloxetine and sildenafil.