Chemical name:(Z)-2-[4-(1,2-Diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine
Formula: C26H29NO
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid

NOLVADEX 10mg – ASTRAZENECA

Description:

Nolvadex 10mg, manufactured by AstraZeneca, contains the active substance tamoxifen citrate. It is a medication commonly used in the treatment and prevention of certain types of breast cancer. Each pack consists of 30 pills, with each pill containing 10 mg of tamoxifen citrate.

Indications:

• Nolvadex 10mg is indicated for various conditions related to breast cancer, including the treatment of metastatic breast cancer, adjuvant treatment of early-stage estrogen receptor-positive breast cancer after surgery and radiation, and reducing the risk of breast cancer in high-risk individuals.

Mechanism of Action:

• Tamoxifen citrate, the active ingredient in Nolvadex, works by selectively binding to estrogen receptors in breast tissue, thereby blocking the effects of estrogen. This action inhibits the growth of estrogen-sensitive breast cancer cells and reduces the risk of cancer recurrence or development.

Administration:

• Nolvadex 10mg is administered orally in the form of tablets. The dosage and duration of treatment may vary depending on the specific indication, the patient’s medical history, and individual response to therapy. It is essential to follow the prescribed regimen provided by a healthcare professional.

Dosage:

• The typical dosage of Nolvadex 10mg for the treatment of breast cancer may range from 20 to 40 mg per day, divided into two doses. For the prevention of breast cancer, a lower dosage may be used. Dosage adjustments may be necessary based on individual patient factors and response to treatment.

Side Effects:

• Common side effects of Nolvadex 10mg may include hot flashes, vaginal discharge or bleeding, nausea, fatigue, and mood changes. More severe side effects, although rare, may include blood clots, stroke, uterine cancer, and cataracts. It is essential to report any persistent or bothersome side effects to a healthcare provider.

Contraindications and Precautions:

• Nolvadex 10mg is contraindicated in individuals with a history of hypersensitivity to tamoxifen citrate or any other components of the formulation. It should be used with caution in patients with a history of blood clots, stroke, or other cardiovascular risk factors. Regular monitoring may be necessary during treatment.

Drug Interactions:

• Nolvadex 10mg may interact with certain medications, including selective serotonin reuptake inhibitors (SSRIs), warfarin, and aromatase inhibitors, among others. It is essential to inform a healthcare provider about all medications, supplements, and herbal products being taken before starting treatment with Nolvadex.

Storage:

• Nolvadex 10mg should be stored at room temperature (between 15°C and 30°C) away from moisture and heat. Keep the medication out of reach of children and pets. Do not use Nolvadex after the expiration date printed on the packaging.

Patient Counseling:

• Patients prescribed Nolvadex 10mg should be counseled on the proper use of the medication, including dosage instructions, potential side effects, and the importance of regular follow-up appointments with a healthcare provider. It is crucial to adhere to the prescribed regimen and report any concerns promptly.