Buy Palynziq (pegvaliase-pqpz) Online

Buy Palynziq (pegvaliase-pqpz) Online

From $330.00

DISEASE INDICATIONS: phenylketonuria (PKU)

MANUFACTURER: BioMarin Pharmaceutical Inc.

USAGE: Subcutaneous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Palynziq (pegvaliase-pqpz) is a prescription medicine used to treat phenylketonuria (PKU) in adults who have uncontrolled blood phenylalanine levels on existing management.

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Description

Palynziq (pegvaliase-pqpz) is a prescription medicine used to treat phenylketonuria (PKU) in adults who have uncontrolled blood phenylalanine levels on existing management. PKU is a genetic disorder that causes the body to not be able to break down the amino acid phenylalanine. This can lead to a buildup of phenylalanine in the blood and brain, which can cause serious health problems, including intellectual disability.

Uses

Palynziq is used to treat adults with PKU who have uncontrolled blood phenylalanine levels on existing management. Existing management may include diet, phenylalanine-restricted medical foods, and large neutral amino acids (LNAAs).

How to Use

Palynziq is administered as a subcutaneous injection once daily. The starting dose is 20 mg. The dose may be increased to 40 mg or 60 mg once daily, depending on the patient’s response.

Dosage

The recommended starting dose of Palynziq is 20 mg administered as a single subcutaneous injection once daily. The dose may be increased to 40 mg or 60 mg once daily, depending on the patient’s response.

Mechanism of Action

Palynziq is a phenylalanine ammonia lyase (PAL) enzyme. PAL is the enzyme that breaks down phenylalanine in the body. Palynziq works by replacing the missing or deficient PAL enzyme in people with PKU. This helps to lower blood phenylalanine levels.

Storage Conditions

Palynziq should be stored in the refrigerator (2-8°C or 36-46°F) in its original carton to protect from light. Do not freeze.

Precautions

  • Palynziq should not be used in people who are allergic to pegvaliase-pqpz or any of the other ingredients in Palynziq.
  • Palynziq should be used with caution in people with liver disease or kidney disease.
  • Palynziq should not be used in pregnant or breastfeeding women.

Interactions

Palynziq may interact with other medications, including certain antibiotics and antifungals. It is important to tell your healthcare provider about all of the medications you are taking before starting Palynziq.

Contraindications

Palynziq is contraindicated in people who are allergic to pegvaliase-pqpz or any of the other ingredients in Palynziq.

Side Effects

The most common side effects of Palynziq are:

  • Injection site reactions (pain, redness, swelling)
  • Headache
  • Fatigue
  • Nausea
  • Diarrhea

Overdose

There is no information on the overdose of Palynziq. However, if you think you have overdosed on Palynziq, contact your healthcare provider or poison control center immediately.

Please note that this is not a complete list of all the information you need to know about Palynziq. Be sure to talk to your healthcare provider for more information and to see if Palynziq is right for you.

Additional Information

Package

1 single-dose prefilled syringe of 2.5 mg/0.5 mL, 1 single-dose prefilled syringe of 10 mg/0.5 mL, 1 single-dose prefilled syringe of 20 mg/1 mL, 10 single-dose prefilled syringes of 20 mg/1 mL

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