Indications:

• Priligy (dapoxetine) is indicated for the treatment of premature ejaculation (PE) in adult men aged 18 to 64 years. Premature ejaculation is characterized by uncontrollable ejaculation that occurs shortly after penetration or before the individual wishes it, leading to distress and frustration.

Mechanism of Action:

• Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) with a rapid onset of action. It works by inhibiting the reuptake of serotonin, a neurotransmitter involved in the regulation of ejaculation. By increasing serotonin levels in the brain, dapoxetine helps delay ejaculation and improve control over ejaculation.

Dosage and Administration:

• The recommended dosage of Priligy may vary depending on individual response and tolerability. It is typically taken orally as needed, approximately 1 to 3 hours before anticipated sexual activity. The tablet should be swallowed whole with a full glass of water, and it can be taken with or without food. The maximum recommended dosing frequency is once per day.

Efficacy:

• Clinical studies have demonstrated the efficacy of dapoxetine in prolonging intravaginal ejaculatory latency time (IELT) and improving control over ejaculation in men with premature ejaculation. It has been shown to increase the time to ejaculation and improve sexual satisfaction in both the patient and his partner.

Side Effects:

• Common side effects of Priligy may include nausea, headache, dizziness, fatigue, insomnia, and dry mouth. These side effects are usually mild to moderate in severity and transient, resolving with continued use or upon discontinuation of the medication.

Precautions:

• Before starting Priligy therapy, patients should undergo a thorough medical evaluation, including assessment of cardiovascular risk factors and any underlying medical conditions. It should be used with caution in patients with a history of orthostatic hypotension, seizure disorders, or psychiatric disorders.

Contraindications:

• Priligy is contraindicated in individuals with a known hypersensitivity to dapoxetine or any of the other components of the medication. It should not be used in patients with significant cardiovascular disease, including heart failure, arrhythmias, or unstable angina.

Storage:

• Priligy tablets should be stored as per the manufacturer’s recommendations, protected from light and moisture, and stored at room temperature.

Priligy (dapoxetine) provides an effective treatment option for men with premature ejaculation, helping to improve control over ejaculation and enhance sexual satisfaction. However, its use should be carefully managed and monitored by qualified healthcare professionals to ensure optimal safety and efficacy for individual patients. Regular follow-up visits may be recommended to assess treatment response and adjust therapy as needed.