Relumina (relugolix) is an orally active, GnRH receptor antagonist that is used to treat endometriosis and heavy menstrual bleeding associated with uterine fibroids. It works by blocking the release of gonadotropin-releasing hormone (GnRH), which reduces the production of estrogen and testosterone.

Description

Relumina is a white to off-white, round, biconvex, film-coated tablet that is available in 40 mg and 20 mg strengths.

Uses

Relumina is used to treat:

• Endometriosis: Endometriosis is a condition in which endometrial tissue, the tissue that normally lines the uterus, grows outside of the uterus. This can cause pain, heavy menstrual bleeding, and infertility.
• Heavy menstrual bleeding associated with uterine fibroids: Uterine fibroids are non-cancerous growths in the uterus. They can cause heavy menstrual bleeding, pelvic pain, and pressure on the bladder or intestines.

How to Use

Relumina is taken orally once a day, with or without food. The recommended starting dose for endometriosis and heavy menstrual bleeding associated with uterine fibroids is 40 mg once a day. The dose may be reduced to 20 mg once a day if needed.

Dosage

The recommended starting dose for endometriosis and heavy menstrual bleeding associated with uterine fibroids is 40 mg once a day. The dose may be reduced to 20 mg once a day if needed.

Mechanism of Action

Relumina works by blocking the release of gonadotropin-releasing hormone (GnRH). GnRH is a hormone that is produced by the hypothalamus and stimulates the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH). LH and FSH are hormones that are essential for ovulation and the production of estrogen and testosterone. By blocking the release of GnRH, Relumina reduces the production of estrogen and testosterone.

Storage Conditions

Relumina should be stored at room temperature (68-77 degrees Fahrenheit) and protected from light and moisture.

Precautions

Relumina should not be used in women who are pregnant or breastfeeding. It should also be used with caution in women with a history of heart disease, stroke, or blood clots.

Interactions

Relumina may interact with other medications, such as birth control pills, hormone therapy, and blood thinners. It is important to tell your doctor about all of the medications you are taking before starting Relumina.

Contraindications

Relumina is contraindicated in women who are pregnant or breastfeeding. It is also contraindicated in women with a history of serious allergic reaction to relugolix or any of the ingredients in Relumina.

Side Effects

The most common side effects of Relumina are headache, hot flashes, vaginal dryness, and decreased libido. Other possible side effects include mood changes, sleep disturbances, nausea, vomiting, and weight changes.

Overdose

There have been no reports of overdose with Relumina. However, if you overdose on Relumina, you should contact your doctor or poison control center immediately.

Additional Information

Relumina is a prescription medication and can only be obtained with a prescription from your doctor. It is important to discuss the risks and benefits of Relumina with your doctor before starting treatment.