Description:

Resof Total is a pharmaceutical product that combines two active ingredients: velpatasvir and sofosbuvir. It is used in the treatment of chronic hepatitis C virus (HCV) infection. Velpatasvir and sofosbuvir belong to a class of medications known as direct-acting antivirals (DAAs) and work by targeting specific proteins essential for the replication of the hepatitis C virus.

Key Points:

• Active Ingredients:
  • Velpatasvir: An inhibitor of the hepatitis C virus NS5A protein, which is essential for viral replication.
  • Sofosbuvir: An inhibitor of the hepatitis C virus NS5B RNA-dependent RNA polymerase, which is also essential for viral replication.
• Indications:
  • Resof Total is indicated for the treatment of chronic hepatitis C virus (HCV) infection in adults.
• Mechanism of Action:
  • Velpatasvir inhibits the NS5A protein, which is involved in the replication of the hepatitis C virus.
  • Sofosbuvir inhibits the NS5B RNA-dependent RNA polymerase, another protein necessary for viral replication. By blocking these proteins, velpatasvir and sofosbuvir prevent the hepatitis C virus from replicating and spreading in the body.
• Dosage Forms:
  • Resof Total is available in oral tablet form, typically supplied in packs containing 28 tablets.
• Dosage and Administration:
  • The dosage of Resof Total is determined by a healthcare professional based on factors such as the genotype of the hepatitis C virus, the patient’s liver function, and prior treatment history. It is usually taken orally once daily with or without food.
• Duration of Treatment:
  • The duration of treatment with Resof Total may vary depending on factors such as the genotype of the hepatitis C virus, the presence of liver cirrhosis, and prior treatment history. Treatment duration typically ranges from 12 to 24 weeks.
• Precautions:
  • Resof Total should be used under the supervision of a qualified healthcare professional experienced in the management of hepatitis C. It is important to inform the healthcare provider about any pre-existing medical conditions, allergies, or medications being taken.
• Possible Side Effects:
  • Common side effects may include headache, fatigue, nausea, and insomnia. Serious side effects such as liver problems and allergic reactions may occur but are rare.
• Monitoring:
  • Regular monitoring of liver function and viral load is typically conducted during Resof Total treatment to assess its effectiveness and monitor for potential side effects.
• Manufacturer:
  • Resof Total is manufactured by Dr. Reddy’s Laboratories Ltd., among other pharmaceutical companies.
• Legal Status:
  • Resof Total is a prescription medication and should only be used under the supervision of a qualified healthcare professional.

Note: Resof Total represents a significant advancement in the treatment of chronic hepatitis C virus infection, offering high efficacy and improved tolerability compared to previous treatment options. Patients should strictly adhere to their healthcare provider’s instructions regarding dosage, administration, and monitoring. Open communication with the healthcare team is crucial to address any concerns or potential side effects during the course of treatment.