Indications:

• Rolimus, with the active ingredient everolimus, is used for various medical purposes, including:
  • Prevention of organ rejection in kidney transplant recipients.
  • Treatment of certain types of advanced cancers, such as renal cell carcinoma, pancreatic neuroendocrine tumors, and certain types of breast cancer.
  • Treatment of non-cancerous conditions like subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex (TSC).

Mechanism of Action:

• Everolimus inhibits the activity of mTOR, a protein kinase that plays a crucial role in cell growth, proliferation, and angiogenesis. By inhibiting mTOR, Rolimus helps control abnormal cell growth seen in both transplanted organs and certain cancers.

Administration:

• Rolimus is typically administered orally in the form of tablets. The dosage and treatment plan are determined by the healthcare provider based on the specific condition being treated and the patient’s individual response.

Dosage Forms:

• The description mentions “Everolimus 5 mg Tablets,” indicating that the tablets contain 5 mg of everolimus.

Dosage and Treatment Plan:

• The dosage and treatment plan with Rolimus depend on the indication, the type of transplant (if applicable), and the specific characteristics of the patient. It is important for patients to adhere to the prescribed dosage and schedule.

Side Effects:

• Common side effects of everolimus may include mouth sores, diarrhea, fatigue, and skin rash. Serious side effects, such as an increased risk of infections and changes in blood cell counts, may also occur. Patients are advised to report any unusual or severe side effects to their healthcare provider.

Precautions:

• Everolimus may interact with other medications, and certain pre-existing conditions may require adjustments to the treatment plan. Regular monitoring of blood counts, kidney function, and blood lipid levels is often recommended.

Consultation with a Healthcare Provider:

• Before starting Rolimus treatment, patients should have a comprehensive consultation with their healthcare provider. The healthcare team will assess the patient’s overall health, medical history, and the specific characteristics of the condition being treated.

Pregnancy and Contraindications:

• Everolimus may cause harm to a developing fetus, and it is generally contraindicated during pregnancy. Women of childbearing potential should use effective contraception during Rolimus treatment.

Patients should always consult with their healthcare provider for personalized advice, including information on dosage, side effects, and potential interactions. The details provided here are general in nature, and the specific prescribing information may vary based on the region and formulation.