Description: Sildamix 10x160mg is a medication manufactured by Zenit Pharma. It is available in tablet form, with each tablet containing 160mg of the active substance sildenafil, commonly known by its brand name Viagra. Sildenafil is a medication used to treat erectile dysfunction (ED) in men by improving blood flow to the penis, thereby facilitating the achievement and maintenance of erections during sexual stimulation.

Active Substance:

• Sildenafil: Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor that works by inhibiting the enzyme PDE5, which regulates blood flow in the penis. By blocking PDE5, sildenafil increases the levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation and vasodilation in the penile arteries, allowing increased blood flow and the formation of erections.

Manufacturer / Brand:

• Zenit Pharma: Zenit Pharma is the manufacturer of Sildamix 10x160mg. It is a pharmaceutical company known for producing various medications, including those for the treatment of erectile dysfunction and other medical conditions.

Uses: Sildamix 10x160mg (sildenafil) is primarily prescribed for the following purpose:

1. Erectile Dysfunction Treatment: It is used to treat erectile dysfunction (ED) in men, a common sexual dysfunction characterized by the inability to achieve or maintain erections sufficient for satisfactory sexual performance.

How to Use: Sildamix 10x160mg tablets are taken orally, usually 30 minutes to 1 hour before anticipated sexual activity, with a full glass of water. The dosage may vary depending on individual response and tolerance, but the maximum recommended dose is usually 100mg per day. It is important to follow the prescribing healthcare provider’s instructions carefully.

Storage Conditions: Sildamix 10x160mg tablets should be stored at room temperature, away from moisture, heat, and direct sunlight. It is essential to keep the medication out of reach of children and pets.

Mechanism of Action: Sildenafil works by selectively inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. By blocking PDE5, sildenafil increases cGMP levels, leading to smooth muscle relaxation and vasodilation in the penile arteries, which enhances blood flow and facilitates the formation of erections during sexual stimulation.

Precautions:

• Patients with a history of cardiovascular disease, liver or kidney impairment, or certain medical conditions should use sildenafil cautiously and under the supervision of a healthcare provider.
• Sildenafil should not be used concurrently with nitrates or alpha-blockers due to the risk of potentially serious interactions.

Contraindications: Sildamix 10x160mg is contraindicated in individuals with a known hypersensitivity to sildenafil or any component of the formulation. It should not be used in patients who are taking nitrate medications for chest pain or heart problems, as this can cause a sudden and severe drop in blood pressure.

Drug Interactions: Sildenafil may interact with certain medications, including nitrates, alpha-blockers, antifungal agents, and certain antibiotics. Patients should inform their healthcare provider about all medications they are taking to avoid potential interactions.

Side Effects: Common side effects of sildenafil may include headache, flushing, indigestion, nasal congestion, and dizziness. Other potential side effects include blurred vision, changes in color vision, and priapism (prolonged erection). Serious adverse reactions such as cardiovascular events and sudden hearing loss may occur but are rare.

Patients should consult their healthcare provider for personalized advice and information regarding Sildamix 10x160mg (sildenafil), including its uses, dosage, and potential side effects.