Stelara is a medication with the generic name ustekinumab, and it is available in the form of an injection. It is a biologic therapy used to treat various autoimmune and inflammatory conditions. Here is a comprehensive description of Stelara (ustekinumab) injection:

Mechanism of Action: Stelara is a biologic medication that targets specific proteins in the immune system called interleukin-12 (IL-12) and interleukin-23 (IL-23). By inhibiting these proteins, it helps regulate the immune response and reduce inflammation associated with autoimmune diseases.

Indications: Stelara is approved for the treatment of several conditions, including:

• Psoriasis: Stelara is used to treat moderate to severe plaque psoriasis in adults and children aged 6 years and older.
• Psoriatic Arthritis: It is indicated for the treatment of active psoriatic arthritis in adults.
• Crohn’s Disease: Stelara can be prescribed to induce and maintain clinical response and remission in adults with moderate to severe Crohn’s disease.
• Ulcerative Colitis: It is also approved for the treatment of moderately to severely active ulcerative colitis in adults.

Dosage: The dosage of Stelara and the frequency of injections depend on the specific condition being treated, the patient’s weight, and other individual factors. A healthcare provider will determine the appropriate dosage and treatment regimen.

Administration: Stelara is administered as a subcutaneous injection, meaning it is injected just under the skin. The injection can be self-administered by the patient or administered by a healthcare professional.

Efficacy: Clinical trials have shown that Stelara is effective in reducing the symptoms and inflammation associated with psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis in many patients.

Side Effects: Common side effects of Stelara may include upper respiratory tract infections, headache, and injection site reactions (such as redness or swelling at the injection site). Serious side effects, including serious infections, malignancies, and allergic reactions, may occur but are relatively rare.

Precautions: Patients should inform their healthcare provider about their complete medical history, current medications, and any allergies before starting Stelara. Regular monitoring and follow-up appointments are essential for assessing the medication’s safety and effectiveness.

Contraindications: Stelara is contraindicated in individuals with a known hypersensitivity to ustekinumab or any of its components. It should not be used in patients with active tuberculosis or other severe infections.

Storage: Stelara should be stored at the recommended temperature, as specified in the medication’s packaging instructions.

Compliance: Patients should adhere to their healthcare provider’s recommendations regarding the use of Stelara to achieve the best therapeutic outcomes.

Stelara (ustekinumab) injection is an important treatment option for individuals with autoimmune and inflammatory conditions, offering relief from symptoms and the potential for improved quality of life. It is crucial to consult with a qualified healthcare provider for a thorough evaluation and a personalized treatment plan before using this medication, as they can provide specific guidance based on individual health needs and circumstances.