Chemical name: (6R-trans)-6-(1,3-benzodioxol-5-yl)- 2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino [1′, 2′
Formula: C22H19N3O4
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid

TADARISE PRO-20 (SUBLINGUAL)

Description: TADARISE PRO-20 (SUBLINGUAL) is a medication manufactured by Sunrise Remedies. It is available in sublingual tablet form, with each tablet containing 20mg of the active substance Tadalafil. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor commonly used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) in men.

Active Substance:

• Tadalafil: Tadalafil is a medication that belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors. It works by inhibiting the enzyme PDE5, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. By blocking PDE5, tadalafil increases cGMP levels, leading to smooth muscle relaxation and vasodilation in the penile arteries, which enhances blood flow and facilitates the formation of erections during sexual stimulation.

Manufacturer / Brand:

• Sunrise Remedies: Sunrise Remedies is the manufacturer of TADARISE PRO-20 (SUBLINGUAL). It is a pharmaceutical company known for producing various medications, including those for the treatment of erectile dysfunction and other medical conditions.

Form:

• 10 pills x 20 mg: This indicates that each pack of TADARISE PRO-20 (SUBLINGUAL) contains 10 sublingual tablets, with each tablet containing 20mg of tadalafil.

Uses: TADARISE PRO-20 (SUBLINGUAL) is primarily prescribed for the following purposes:

1. Erectile Dysfunction Treatment: It is used to treat erectile dysfunction (ED) in men, a common sexual dysfunction characterized by the inability to achieve or maintain erections sufficient for satisfactory sexual performance.
2. Benign Prostatic Hyperplasia Treatment: In some cases, tadalafil may also be used to treat symptoms of benign prostatic hyperplasia (BPH), such as difficulty urinating and urinary frequency.

How to Use: TADARISE PRO-20 (SUBLINGUAL) tablets are designed to be taken sublingually, which means they are placed under the tongue and allowed to dissolve without swallowing. The tablet should be placed under the tongue, where it will dissolve rapidly, and the medication will be absorbed directly into the bloodstream. The dosage and timing of administration may vary depending on individual response and tolerance. It is important to follow the prescribing healthcare provider’s instructions carefully.

Storage Conditions: TADARISE PRO-20 (SUBLINGUAL) tablets should be stored at room temperature, away from moisture, heat, and direct sunlight. It is essential to keep the medication out of reach of children and pets.

Mechanism of Action: Tadalafil works by selectively inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. By blocking PDE5, tadalafil increases cGMP levels, leading to smooth muscle relaxation and vasodilation in the penile arteries, which enhances blood flow and facilitates the formation of erections during sexual stimulation.

Precautions:

• Patients with a history of cardiovascular disease, liver or kidney impairment, or certain medical conditions should use tadalafil cautiously and under the supervision of a healthcare provider.
• Tadalafil should not be used concurrently with nitrates or alpha-blockers due to the risk of potentially serious interactions.

Contraindications: TADARISE PRO-20 (SUBLINGUAL) is contraindicated in individuals with a known hypersensitivity to tadalafil or any component of the formulation. It should not be used in patients who are taking nitrate medications for chest pain or heart problems, as this can cause a sudden and severe drop in blood pressure.

Drug Interactions: Tadalafil may interact with certain medications, including nitrates, alpha-blockers, antifungal agents, and certain antibiotics. Patients should inform their healthcare provider about all medications they are taking to avoid potential interactions.

Side Effects: Common side effects of tadalafil may include headache, flushing, indigestion, nasal congestion, and dizziness. Other potential side effects include blurred vision, changes in color vision, and priapism (prolonged erection). Serious adverse reactions such as cardiovascular events and sudden hearing loss may occur but are rare.

Patients should consult their healthcare provider for personalized advice and information regarding TADARISE PRO-20 (SUBLINGUAL), including its uses, dosage, and potential side effects.