Chemical name:(Z)-2-[4-(1,2-Diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine
Formula: C26H29NO
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
TAMOXIFEN 20mg – PARA PHARMA
Tamoxifen citrate is a medication that is commonly used in the treatment of hormone receptor-positive breast cancer. It is classified as a selective estrogen receptor modulator (SERM) and is used primarily in both adjuvant and preventive settings. Tamoxifen citrate works by blocking the effects of estrogen in certain tissues, inhibiting the growth of hormone-sensitive breast cancer cells.
Here is a general description of Tamoxifen Citrate:
Generic Name: Tamoxifen Citrate
Class: Selective Estrogen Receptor Modulator (SERM)
Indications:
- Breast Cancer Treatment: Tamoxifen is used in the treatment of hormone receptor-positive breast cancer, either as adjuvant therapy following surgery or other treatments or for metastatic breast cancer.
- Breast Cancer Prevention: It may also be used for the prevention of breast cancer in high-risk individuals.
Mechanism of Action: Tamoxifen is a SERM that acts by selectively blocking estrogen receptors in breast tissue. It competes with estrogen for binding to these receptors, preventing estrogen from stimulating the growth of hormone-sensitive breast cancer cells.
Administration: Tamoxifen citrate is administered orally in the form of tablets.
Dosage: The dosage can vary based on the specific characteristics of the breast cancer being treated or the individual’s risk factors for breast cancer prevention. Dosages are often 20 mg taken once daily.
Efficacy: Tamoxifen has been shown to be effective in reducing the risk of recurrence in hormone receptor-positive breast cancer and is considered a standard adjuvant therapy.
Common Side Effects:
- Hot flashes
- Vaginal discharge or dryness
- Mood swings
- Nausea
- Menstrual irregularities (in premenopausal women)
Precautions:
- Tamoxifen should be used with caution in patients with a history of blood clots or other thromboembolic events.
- Regular gynecological check-ups are recommended due to a potential increased risk of endometrial cancer.
- It may interact with other medications, and patients should inform their healthcare provider of all medications they are taking.
- Tamoxifen should not be used during pregnancy.
Tamoxifen is an important medication in the treatment and prevention of breast cancer, particularly in individuals with hormone receptor-positive tumors. It is typically prescribed based on an individual’s specific medical history, the characteristics of the breast cancer, and considerations related to risk and benefit. Patients should follow their healthcare provider’s instructions closely and report any side effects or concerns during treatment. Regular monitoring and follow-up appointments are essential for individuals on tamoxifen therapy.
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