1. Active Substance:
   • Tilidin is the active ingredient in Tilidin 20 x 150/12mg. It is an opioid analgesic medication used for the treatment of moderate to severe pain. Tilidin is a synthetic opioid that acts centrally on the nervous system to relieve pain.
2. Medical Uses:
   • Pain Management: Tilidin is indicated for the relief of moderate to severe pain, such as that experienced after surgery, injury, or in chronic conditions like cancer-related pain.
   • Combination Therapy: Tilidin is often formulated in combination with other medications, such as naloxone, to reduce the risk of abuse and dependence.
3. Mode of Action:
   • Tilidine works by binding to opioid receptors in the brain and spinal cord, thereby inhibiting the transmission of pain signals and altering the perception of pain. It also has a central nervous system depressant effect, leading to sedation and relaxation.
4. Dosage and Administration:
   • The dosage of Tilidin 20 x 150/12mg is determined by a healthcare professional based on factors such as the severity of pain, the patient’s medical history, and individual response to treatment.
   • It is typically administered orally in the form of tablets, with dosages adjusted according to the patient’s needs and tolerance. The tablets may be taken with or without food, as directed by the prescribing physician.
5. Side Effects:
   • Common side effects of Tilidin may include:
     • Nausea and vomiting
     • Dizziness or lightheadedness
     • Sedation or drowsiness
     • Constipation
     • Sweating or flushing
     • Itching or skin rash
   • Serious side effects may occur with prolonged or high-dose use, including respiratory depression, dependence, and addiction.
6. Precautions:
   • Tilidin should be used with caution in patients with a history of substance abuse or addiction, as it has the potential for abuse, dependence, and addiction.
   • It is important to follow proper dosage guidelines and avoid exceeding the recommended dose or duration of treatment to minimize the risk of adverse effects.
   • Tilidin should not be used in patients with severe respiratory depression, acute asthma, or other respiratory conditions that may be exacerbated by opioid therapy.
7. Prescription Required:
   • Yes, Tilidin is a prescription medication, and its use should be guided by a healthcare professional’s prescription.
8. Note:
   • Tilidin is classified as a controlled substance in many countries due to its potential for abuse and addiction. It should be used with caution and only under the supervision of a qualified healthcare professional.
   • Patients prescribed Tilidin should be monitored closely for signs of respiratory depression, sedation, and other adverse effects. Regular assessment of pain control and adjustment of treatment as necessary are important aspects of pain management with opioids.

It’s essential for individuals prescribed Tilidin to follow their healthcare provider’s instructions carefully, report any side effects or concerns promptly, and avoid alcohol and other central nervous system depressants while taking this medication. Misuse or abuse of Tilidin can lead to serious health consequences and legal ramifications.