What is the purpose of Tyrvaya (varenicline solution)?

Tyrvaya (varenicline solution) is a medication that targets dry eye disease symptoms as it increases tear production by activating the trigeminal parasympathetic pathway. Each tablet form consists of 60 sprays of the active ingredient varenicline.

How does Tyrvaya (varenicline solution) function?

Dry eye disease results from the inadequate production of the correct tear type, creating tear film inconsistencies. The rest and digest system, or the parasympathetic nervous system, is responsible for regulating tear film homeostasis. The trigeminal parasympathetic pathway in the nose also contributes to this system. By stimulating this pathway, Tyrvaya’s active ingredient, varenicline, increases tear film production. The mechanism of Tyrvaya’s actions is not entirely known.

Where is Tyrvaya (varenicline solution) approved?

The FDA has approved Tyrvaya (varenicline solution) for treating dry eye disease. However, the medication may have approval in other regions as well.

What are the standard dosage instructions of Tyrvaya (varenicline solution)?

The prescribed dosage is once in each nostril, twice a day, 12 hours apart, containing 0.03mg of the spray. If a dose is missed, you can resume regular dosage at the next scheduled time. Consult your doctor for personalized dosing.

What are the side effects of Tyrvaya (varenicline solution)?

The most common side effects listed in the prescribing information include sneezing, cough, throat irritation, and nose irritation. It is uncertain whether the medication would harm an unborn baby as it did not cause any adverse effects in animal studies. For detailed information about the drug’s side effects and reactions, refer to the official prescribing instructions.