Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid

VIGORA-50

Overview

VIGORA-50 is a pharmaceutical product containing Sildenafil Citrate, a widely recognized and effective treatment for erectile dysfunction (ED) in men. Each tablet is formulated with 50 mg of Sildenafil Citrate, designed to help men achieve and maintain a firm erection suitable for sexual activity. Manufactured by German Remedies, a reputable pharmaceutical company known for its commitment to quality and safety, VIGORA-50 is a trusted option for those experiencing challenges with erectile function.

What is Sildenafil Citrate?

Sildenafil Citrate, the active ingredient in VIGORA-50, is a type of medication known as a phosphodiesterase type 5 (PDE5) inhibitor. It works by relaxing the smooth muscles found in the walls of blood vessels, specifically in the penile region. This relaxation leads to increased blood flow to the penis, which is essential for achieving an erection. Sildenafil Citrate was originally developed to treat cardiovascular conditions such as hypertension and angina, but its efficacy in treating erectile dysfunction was discovered during clinical trials.

How Does VIGORA-50 Work?

VIGORA-50 works by targeting the PDE5 enzyme, which plays a significant role in regulating blood flow to the penis. During sexual stimulation, nitric oxide is released into the penile tissue, activating an enzyme called guanylate cyclase. This enzyme increases levels of cyclic guanosine monophosphate (cGMP), which relaxes smooth muscle cells and enhances blood flow to the penis, resulting in an erection. Sildenafil Citrate inhibits the PDE5 enzyme, preventing the breakdown of cGMP, thereby promoting sustained blood flow and a firm erection.

Indications and Usage

VIGORA-50 is primarily indicated for the treatment of erectile dysfunction in men. Erectile dysfunction, commonly referred to as impotence, is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. VIGORA-50 helps men with ED by improving erectile response when sexual stimulation occurs. It is important to note that VIGORA-50 will not produce an erection without sexual arousal.

Dosage and Administration

The recommended dosage of VIGORA-50 is one tablet taken approximately one hour before sexual activity. It is important to follow the dosage instructions provided by a healthcare professional. The tablet should be swallowed whole with water and can be taken with or without food. However, a high-fat meal may delay the onset of action. It is advisable not to take more than one tablet in a 24-hour period.

Duration of Effect

The effects of VIGORA-50 can last for up to four hours. However, this does not mean that an erection will be sustained for this duration. Rather, it means that the ability to achieve an erection may be improved for up to four hours after taking the tablet, provided there is sexual stimulation. The onset of action usually occurs within 30 to 60 minutes.

Who Should Not Use VIGORA-50?

VIGORA-50 is not suitable for everyone. It should not be used by individuals who:

• Are allergic to Sildenafil Citrate or any other components of the tablet.
• Are taking nitrates, often prescribed for chest pain (angina), or certain recreational drugs known as “poppers” (e.g., amyl nitrate or nitrite), as the combination can cause a dangerous drop in blood pressure.
• Have been advised by a doctor to avoid sexual activity due to cardiovascular risk factors.
• Have severe heart or liver problems.
• Have recently had a stroke or heart attack, or have low blood pressure.
• Have certain rare inherited eye diseases (such as retinitis pigmentosa).

Possible Side Effects

Like all medications, VIGORA-50 can cause side effects, although not everyone will experience them. Common side effects may include:

• Headache
• Flushing
• Upset stomach
• Nasal congestion
• Dizziness
• Visual disturbances (e.g., changes in color vision, blurred vision)

Rare but serious side effects can include sudden hearing loss, an erection that is painful or lasts longer than 4 hours (priapism), and sudden vision loss in one or both eyes (non-arteritic anterior ischemic optic neuropathy or NAION). If any of these serious side effects occur, immediate medical attention is required.

Interactions with Other Medications

VIGORA-50 may interact with certain medications, potentially altering their effects or increasing the risk of adverse reactions. It is crucial to inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, herbal supplements, and vitamins. Significant interactions may occur with:

• Nitrates (for chest pain)
• Alpha-blockers (for high blood pressure or prostate problems)
• Other medications used to treat erectile dysfunction
• Protease inhibitors (used to treat HIV)
• Certain antifungal and antibiotic medications

Storage Instructions

VIGORA-50 should be stored in its original packaging at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use VIGORA-50 past its expiration date as stated on the packaging.

Important Considerations

• Consultation with a Healthcare Provider: Before starting VIGORA-50, it is essential to consult with a healthcare provider to ensure it is safe and appropriate for your condition.
• Sexual Stimulation Required: VIGORA-50 facilitates erection only with sexual arousal. It does not cause sexual desire.
• Not a Cure for Erectile Dysfunction: While VIGORA-50 helps manage the symptoms of ED, it does not cure the underlying condition or increase sexual desire.
• Lifestyle Factors: For optimal effectiveness, lifestyle changes such as exercising regularly, maintaining a healthy weight, reducing alcohol consumption, and quitting smoking can improve erectile function.

Why Choose VIGORA-50?

VIGORA-50 offers a reliable solution for men experiencing erectile dysfunction, providing a significant improvement in erectile quality and sexual satisfaction. Its 50 mg dosage is often considered an optimal starting dose, balancing effectiveness with the potential for side effects. Produced by German Remedies, a trusted name in pharmaceuticals, VIGORA-50 ensures high standards of quality, safety, and efficacy.

Conclusion

VIGORA-50 (Sildenafil Citrate Tablets IP) is a proven and effective treatment for erectile dysfunction, helping men achieve and maintain erections for satisfactory sexual activity. By inhibiting the PDE5 enzyme and enhancing blood flow to the penis, VIGORA-50 enables men with ED to regain confidence and enjoy improved sexual health. Always consult with a healthcare provider before using VIGORA-50 to ensure it is safe and appropriate for you.