Description:

Volantis is a pharmaceutical product containing the active ingredient everolimus. Everolimus belongs to a class of medications known as mammalian target of rapamycin (mTOR) inhibitors. It is used in the treatment of various types of cancer and certain non-cancerous conditions. Volantis works by inhibiting the mTOR pathway, which is involved in regulating cell growth, proliferation, and angiogenesis.

Key Points:

• Active Ingredient:
  • Everolimus: An mTOR inhibitor that interferes with the mTOR signaling pathway, leading to the inhibition of cell growth and proliferation.
• Indications:
  • Volantis is indicated for the treatment of:
    • Advanced renal cell carcinoma (kidney cancer).
    • Advanced hormone receptor-positive, HER2-negative breast cancer.
    • Advanced pancreatic neuroendocrine tumors.
    • Subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex (TSC).
    • Renal angiomyolipoma with tuberous sclerosis complex (TSC) not requiring immediate surgery.
• Mechanism of Action:
  • Everolimus inhibits the activity of the mTOR protein, which plays a key role in regulating cell growth, proliferation, and angiogenesis. By blocking this pathway, everolimus slows down cancer cell growth and may also prevent the growth of new blood vessels that support tumor growth.
• Dosage Forms:
  • Volantis is available in oral tablet form, with each tablet typically containing 10 mg of everolimus.
• Dosage and Administration:
  • The dosage of Volantis is determined by a healthcare professional based on the type of cancer being treated, the patient’s overall health, and individual response to treatment. The tablets are usually taken orally, with or without food.
• Treatment Duration:
  • The duration of Volantis treatment varies based on the specific cancer being treated and the overall treatment plan devised by the oncologist.
• Precautions:
  • Volantis should be used under the supervision of a qualified healthcare professional. It is important to inform the healthcare provider about any pre-existing medical conditions, allergies, or medications being taken.
• Possible Side Effects:
  • Common side effects may include stomatitis (mouth sores), diarrhea, rash, fatigue, and infections. Serious side effects are possible and should be reported to the healthcare provider promptly.
• Monitoring:
  • Regular monitoring, including imaging studies and blood tests, is typically conducted during Volantis treatment to assess its effectiveness and monitor for potential side effects.
• Manufacturer:
  • The specific manufacturer of Volantis may vary depending on the region and pharmaceutical distributor.
• Legal Status:
  • Volantis is a prescription medication and should only be used under the supervision of a qualified healthcare professional.

Note: Volantis represents an important treatment option for various advanced cancers and certain non-cancerous conditions. Patients should strictly adhere to their healthcare provider’s instructions regarding dosage, administration, and monitoring. Open communication with the healthcare team is crucial to address any concerns or potential side effects during the course of treatment.