Chemical name: (1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine
Formula: C21H23NO
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
VRILIGY-60
1. Active Substance:
- Dapoxetine: Dapoxetine is the active pharmaceutical ingredient in Vriligy-60 tablets. It belongs to a class of medications called selective serotonin reuptake inhibitors (SSRIs). Dapoxetine is specifically approved for the treatment of premature ejaculation (PE). It works by increasing the activity of serotonin in the nervous system, which helps to delay ejaculation and improve control over ejaculation.
2. Indications:
- Premature Ejaculation (PE): Vriligy-60 is indicated for the treatment of premature ejaculation in adult men. Premature ejaculation is a common sexual disorder characterized by the inability to delay ejaculation sufficiently to enjoy satisfactory sexual intercourse. Dapoxetine helps to increase ejaculatory latency time and improve control over ejaculation.
3. Dosage:
- Each Vriligy-60 tablet contains 60 mg of dapoxetine.
- The recommended dosage for the treatment of premature ejaculation is usually 30 mg or 60 mg taken orally as needed, approximately 1 to 3 hours before anticipated sexual activity.
- Treatment should be initiated at the lowest effective dosage, and the maximum recommended dosage should not be exceeded.
4. Administration:
- Vriligy-60 tablets are taken orally with a full glass of water.
- The tablets should be swallowed whole without chewing or crushing.
- It is recommended to take Vriligy-60 with or without food, although taking it with a high-fat meal may delay the onset of action.
5. Effectiveness:
- Vriligy-60 has been shown to be effective in increasing ejaculatory latency time and improving control over ejaculation in men with premature ejaculation.
- Dapoxetine helps to delay ejaculation and prolong the time to ejaculation, leading to greater sexual satisfaction for both the patient and their partner.
6. Safety Profile:
- Vriligy-60 is generally well-tolerated when used as prescribed. Common side effects may include nausea, headache, dizziness, dry mouth, and fatigue.
- Serious side effects such as syncope (fainting), suicidal ideation, and serotonin syndrome are rare but possible.
- Patients should be monitored for signs of adverse reactions, especially when initiating treatment or adjusting dosage.
7. Contraindications:
- Vriligy-60 is contraindicated in patients with known hypersensitivity to dapoxetine or any of the excipients in the formulation.
- It should not be used in patients with significant cardiovascular disease, severe hepatic impairment, or a history of mania/hypomania or bipolar disorder.
8. Precautions:
- Vriligy-60 should be used with caution in patients with a history of bleeding disorders, seizures, or renal impairment.
- It should be avoided in patients taking monoamine oxidase inhibitors (MAOIs) or other medications that affect serotonin levels.
9. Storage:
- Vriligy-60 should be stored at room temperature (15°C to 30°C) in a dry place, away from moisture and heat.
- Keep the medication out of reach of children and pets.
Vriligy-60 tablets, manufactured by Centurion Laboratories, offer an effective treatment option for men with premature ejaculation. Treatment should be initiated and monitored by a qualified healthcare professional, and patients should be informed about potential side effects and precautions associated with the use of dapoxetine.
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