Xatral XL is a medication manufactured by Sanofi, containing the active substance alfuzosin. It is commonly used to treat symptoms of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. Here is a detailed description of Xatral XL:

Form: Xatral XL is available in the form of prolonged-release tablets, typically packaged in a box containing 30 pills, with each pill containing 10 mg of alfuzosin.

Indications:

• Xatral XL (alfuzosin) is indicated for the treatment of benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland that can cause urinary symptoms such as difficulty urinating, frequent urination, and nocturia (excessive urination at night).

Mechanism of Action:

• Alfuzosin belongs to a class of medications known as alpha-1 adrenergic blockers. It works by relaxing the muscles in the prostate gland and the bladder neck, which helps improve urine flow and reduce urinary symptoms associated with BPH.

Dosage and Administration:

• The recommended dosage of Xatral XL may vary depending on the severity of symptoms and individual patient response. It is typically taken orally once daily, preferably after the same meal each day, to ensure consistent absorption and efficacy.

Efficacy:

• Clinical studies have demonstrated the efficacy of alfuzosin in improving urinary symptoms and urinary flow rate in men with benign prostatic hyperplasia. It helps relieve symptoms such as incomplete emptying of the bladder, weak urine stream, and urinary urgency.

Side Effects:

• Common side effects of Xatral XL may include dizziness, headache, fatigue, drowsiness, and nasal congestion. These side effects are usually mild and transient, but some individuals may experience more pronounced symptoms, particularly when starting treatment.

Precautions:

• Before starting Xatral XL, patients should inform their healthcare provider about their complete medical history, current medications, and any allergies. It should be used with caution in patients with certain pre-existing medical conditions, such as hypotension (low blood pressure) or hepatic impairment.

Contraindications:

• Xatral XL is contraindicated in individuals with a known hypersensitivity to alfuzosin or any of the other components of the medication. It should not be used in patients with severe hepatic impairment or in combination with potent CYP3A4 inhibitors.

Storage:

• Xatral XL tablets should be stored as per the manufacturer’s recommendations, protected from light and moisture, and stored at room temperature.

Xatral XL (alfuzosin) provides an effective treatment option for men with benign prostatic hyperplasia, helping to alleviate urinary symptoms and improve quality of life. However, its use should be carefully managed and monitored by qualified healthcare professionals to ensure optimal safety and efficacy for individual patients. Regular follow-up visits may be recommended to assess treatment response and adjust therapy as needed.