Zoryve (roflumilast) is a topical cream that is used to treat plaque psoriasis of the skin and skin folds in adults and children aged 12 years and older. Plaque psoriasis is a chronic autoimmune disease that causes red, scaly patches to form on the skin.

Description

Zoryve is a white, odorless cream that is applied directly to the affected areas of the skin. It is available in a 0.3% strength.

Uses

Zoryve is used to treat plaque psoriasis, which is the most common form of psoriasis. Plaque psoriasis causes red, scaly patches to form on the skin. The patches can be itchy and painful, and they can appear anywhere on the body.

How to Use

Zoryve is applied to the affected areas of the skin once a day. Apply a thin layer of cream to the affected areas and rub it in gently until it is completely absorbed. Zoryve can be used on all areas of the body, including the face, scalp, and skin folds.

Dosage

The recommended dosage of Zoryve is one application per day to the affected areas of the skin.

Mechanism of Action

Zoryve works by inhibiting the activity of phosphodiesterase 4 (PDE4), an enzyme that plays a role in inflammation. By inhibiting PDE4, Zoryve can help to reduce inflammation and improve the appearance of the skin in people with plaque psoriasis.

Storage Conditions

Zoryve should be stored at room temperature (20°C to 25°C). It should not be stored in the refrigerator or freezer.

Precautions

Zoryve should be used with caution in patients with a history of allergic reactions to other topical medications. It is also important to tell your doctor about any other medications you are taking, including over-the-counter medications, herbal supplements, and vitamins.

Interactions

Zoryve may interact with other topical medications that are used to treat psoriasis. It is important to tell your doctor about all of the topical medications you are using before starting Zoryve.

Contraindications

Zoryve is contraindicated in patients with a known hypersensitivity to roflumilast or any of the excipients in the drug.

Side Effects

The most common side effects of Zoryve are mild and transient. The most common side effects include:

• Application site reactions (e.g., redness, itching, burning, stinging)
• Diarrhea
• Headache
• Nausea
• Nasopharyngitis (inflammation of the nose and throat)

Serious side effects of Zoryve are rare. However, serious side effects can occur, including:

• Allergic reactions
• Depression
• Suicidal thoughts and behavior

If you experience any serious side effects while using Zoryve, stop using the medication and contact your doctor immediately.

Overdose

There is no information available on overdose of Zoryve. However, if you accidentally swallow Zoryve, contact your doctor or poison control center immediately.

Additional Information

Zoryve is a relatively new drug, and it is still being studied. However, it has been shown to be effective in treating plaque psoriasis in clinical trials. Zoryve is generally well-tolerated, and the most common side effects are mild and transient.

Please note that this is just a general overview of Zoryve. Before using Zoryve, be sure to talk to your doctor about the risks and benefits of the medication.