As the COVID-19 virus has not been effectively controlled and is still ravaging the world today, a new “superbug” has emerged in the UK – “supergonococcus”. The Health and Safety Agency has discovered a number of cases of gonorrhea, which is resistant to antibiotics, the Daily Mail reported. Britain is on high alert.

Gonorrhoea is the second most common sexually transmitted disease in the UK. It is a suppurative infection of the genitourine tract caused by neisseria gonorrhoeae (also known as Neisseria gonorrhoeae), which is mainly transmitted through unprotected sex. Humans, as the only natural host, can infect the human vagina, mouth, eyes, anus and rectum. At present, the main medical means for its treatment is to timely give sufficient and standardized antibiotic treatment, the preferred antibiotics are the third generation cephalosporin, such as cephalosporin sodium, cefotaxime, etc. For patients who cannot be treated with cephalosporin, azithromycin or metanomycin can be chosen for treatment. And according to the information public health service in England, the super gonorrhea in Britain not only more infectious, and still more tenacious, completely resistant to antibiotics used in treatment of gonorrhea, therefore the British health bureau said to adopt what kind of treatment for the diagnosis of a few cases of those diagnosed in the super gonorrhea treatment is still in the research, is more difficult.

In fact, as early as 2016, the World Health Organization called for active global response to the problem of antibiotic resistance. In recent years, with the increasing resistance of pathogenic bacteria, countries are paying more and more attention to it. At present, there are three main solutions to drug resistance:

1. Strictly control the use of antibiotics

The abuse of antibiotics is the main cause of drug resistance of pathogenic bacteria. Is the production and use of antibiotics in China power, many common diseases, such as chronic prostatitis, chronic pharyngitis, chronic pelvic inflammatory disease, etc., both clinicians and patients themselves are habitually use of antibiotics to treat, but in fact these diseases is not to need to use antibiotic treatment, and long-term so then you are more likely to cause drug resistance problems, so safe and reasonable It is very important to regulate the use of antibiotics. In recent years, the National Health Commission has also issued the National Action Plan for Curbing Bacterial Resistance (2016-2020), The Notice on Continuing to Do a Good job in the Management of Clinical Application of Antibacterial drugs, and the Notice on Improving the Diagnosis and Treatment capacity of Bacterial and Fungal Infections in General Hospitals at or above secondary level to strictly control the use of antibiotics.

Developing new antibiotics

Developing new antibiotics is one way to solve the problem of drug resistance. In order to deal with the increasing resistance of pathogenic bacteria, scientists are actively developing new antibiotics. On August 27, 2018, the U.S. Food and Drug Administration (FDA) approved Biopharmaceutical inc. ‘s pioneering antibiotic Xerava for the treatment of complex intraperitoneal infections in adults. It is reported that this is a new, fully synthetic fluorinated tetracycline antibacterial drug, its antibacterial spectrum is wide, multiple drug resistance gram-negative, gram-positive bacteria and anaerobic bacteria are active. On September 5, 2018, Yun He, professor of Chongqing University, China, and his team also developed a new antibiotic containing apamycin δ1,δ2 and ε, which can kill Streptococcus pneumoniae, Staphylococcus aureus and methicillin-resistant Staphylococcus aureus. In addition, there are many scientists are actively exploring, research and development efforts.

Third, looking for antibiotic substitutes

Given antibiotics has many side effects and disadvantages, so compared with the development of new antibiotics, people prefer to have other medicines to replace antibiotics, but scientists also has carried on the exploration and research, and also made some achievements, such as in 2021, our country’s dragon biological technology research and development team in the past 15 years, fully mastered the technology of gene recombinant human lysozyme and The recombinant human lysozyme has been tested and certified by many authoritative institutions such as Chinese Academy of Sciences and Chinese Center for Disease Control and Prevention. It is believed that “recombinant human lysozyme” has bactericidal, antiviral, anti-inflammatory, phlegm-reducing, analgesic and immunomodulatory functions, and is expected to become a substitute for antibiotics and remedy for the defects of antibiotics in the future. So I believe there will be better drugs to replace antibiotics in the future. But at present, because most scientists are still in the stage of discovery and exploration, there is not much that can be really applied to the clinic, so we still need to wait patiently. Of course, now clinical is not completely without drugs can replace antibiotics, part of the heat and detoxification effect of traditional Chinese medicine can achieve antibacterial and anti-toxic effects of antibiotics, such as honeysuckle, forsythia, isatidis root, etc.. Like the treatment of gonorrhea mentioned at the beginning of the article, Chinese medicine diuresis anti-inflammatory pills or fuyan pills can play a better effect.

Antibiotic resistance has become a major problem affecting the health of all mankind. Therefore, in order to reduce drug resistance as much as possible, we must use antibiotics rationally, and must not abuse them, so as not to cause superbugs and make ourselves without medicine.

Roids Base

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