DISEASE INDICATIONS: phenylketonuria (PKU) MANUFACTURER: BioMarin Pharmaceutical Inc. USAGE: Subcutaneous MEDICINE APPROVED BY: European Medical Agency (EMA) Food and Drug Administration (FDA) Palynziq (pegvaliase-pqpz) is a prescription medicine used to treat phenylketonuria (PKU) in adults who have uncontrolled blood phenylalanine levels on existing management.